Journal: Molecules

Article Title: In Vitro Anti- Candida Activity and Action Mode of Benzoxazole Derivatives

doi: 10.3390/molecules26165008

Figure Lengend Snippet: UV spectrometric ergosterol content (%) in the benzoxazole-treated C. albicans .

Article Snippet: Antifungal activity of benzoxazole derivatives was tested against the reference Candida albicans SC5314 strain from American Type Culture Collection (ATCC).

Techniques:

Journal: Molecules

Article Title: In Vitro Anti- Candida Activity and Action Mode of Benzoxazole Derivatives

doi: 10.3390/molecules26165008

Figure Lengend Snippet: Ergosterol quantification in the benzoxazole-treated C. albicans using HPLC.

Article Snippet: Antifungal activity of benzoxazole derivatives was tested against the reference Candida albicans SC5314 strain from American Type Culture Collection (ATCC).

Techniques:

Journal: Molecules

Article Title: In Vitro Anti- Candida Activity and Action Mode of Benzoxazole Derivatives

doi: 10.3390/molecules26165008

Figure Lengend Snippet: Benzoxazoles’ influence on the passive efflux of Rho123. Legend: Rhodamine (Rho123) content as a relative difference between the control and test (%) in the post-culture medium of the C. albicans SC5314 treated with compounds 5a , 5e , 5j , 8c , 8h , 8i and 13d at different concentrations. %C = (A(test) − A(control))/A(control) × 100, where A (control) = 3901. The C. albicans cells were incubated with Rho123 at 20 mM for 10 min and the Rho123 extracellular conc. was determined against a standard curve following the cell lysis with Triton 6100. Standard curve: A = 1155.9 C + 3901 → C = A − 3901 1155.9 . Data mean the average of three separate repeats S.D.

Article Snippet: Antifungal activity of benzoxazole derivatives was tested against the reference Candida albicans SC5314 strain from American Type Culture Collection (ATCC).

Techniques: Control, Incubation, Lysis

Journal: Molecules

Article Title: In Vitro Anti- Candida Activity and Action Mode of Benzoxazole Derivatives

doi: 10.3390/molecules26165008

Figure Lengend Snippet: The interaction between benzoxazoles and exogenous ergosterols. Legend: Absorbance at 400nm after 96 h incubation of the C. albicans SC5314 cells in YEPD containing different concentrations of benzoxazoles and exogenous ergosterol. The mean % of absorbance of the growth control is presented as GCW. ITR means Itraconazole. The assay was performed in triplicate. Values are presented as means ± SD.

Article Snippet: Antifungal activity of benzoxazole derivatives was tested against the reference Candida albicans SC5314 strain from American Type Culture Collection (ATCC).

Techniques: Incubation, Control